Absorbed from the gastrointestinal tract, bioavailability – 89%. The equilibrium concentrations are reached within 3 – 5 days. Binding to plasma proteins – 99%. It penetrates through the blood-tissue barriers. Almost completely metabolized in the liver. Deca durabolin for sale. Plasma clearance – 8 ml / min, the elderly decreases. – osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (ankylosing spondylitis) – elimination of pain and inflammation in degenerative and inflammatory joint diseases (including acute attack of gouty arthritis) – lumbago, sciatica, neuralgia, myalgia, diseases of extra-articular and soft tissue hgh factor and xanogen, post-traumatic and post-operative pain
Dosing and Administration The drug is taken orally during a meal once a day.
The recommended dosing regimen – Rheumatoid arthritis: 15 mg / day. Depending on the therapeutic effect, the dose can be reduced to 7.5 mg / day. – Osteoarthritis: 7.5 mg / day. . If necessary, the dose may be increased to 15 mg / day – Ankylosing spondylitis: 15 mg / day.
The maximum recommended daily dose – 15 mg. In patients with an increased risk of side effects, as well as in patients with severe renal impairment on hemodialysis, the dose should not exceed 7.5 mg / day.
Contraindications – hypersensitivity to the drug – aspirin-induced asthma – the aggravation of gastric ulcer and duodenal ulcer – gastrointestinal, deca durabolin for sale cerebrovascular or other bleeding – severe hepatic, cardiac, renal failure (without dialysis) – under 15 years – Pregnancy, lactation
Side effects – diarrhea disorders, gastro – intestinal bleeding; – anemia, – headache, dizziness, disorientation
Interaction with other drugs With simultaneous use of: – other NSAIDs – increased risk of erosive and ulcerative lesions and gastrointestinal bleeding – with antihypertensive drugs – may decrease the effectiveness of the latter – with drugs lithium – can increase its toxic effect – with methotrexate – increased side effects the latter on the hematopoietic system (risk of anemia and leukopenia) – diuretics and cyclosporine – increase the risk of kidney failure – with intrauterine contraceptives – may reduce the effectiveness of the past – with anticoagulants and thrombolytics – increase the risk of bleeding
Cautions – To apply caution in patients with gastric ulcer and duodenal ulcer in the anamnesis, as well as receiving anticoagulant therapy, because of an increased risk of ulcerative erosive gastrointestinal diseases – Monitor renal function when using the drug in elderly patients with chronic heart failure, liver cirrhosis, and in patients who have undergone surgery, which led to hypovolemia – When assigning deca durabolin for sale simultaneously with diuretics, you should take plenty of fluids – like other NSAIDs, may mask the symptoms of infectious diseases buy anabolic steroids online bruce lee’s workout anabolic steroids online uk long term effects of anabolic steroids mike o’hearn natural anabolic steroid pill cheap bodybuilding meals black market pre workout natural bodybuilding diet